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    BIOMARKER:

    TNFRSF1A rs4149570

    i
    Other names: TNFRSF1A, TNF Receptor Superfamily Member 1A, TNFAR, TNF-R-I, TNF-R55, TNFR60, CD120a, TNF-R, TNFR1, Tumor Necrosis Factor Receptor Superfamily Member 1A, TNF-R1, TNF-RI, TNFR-I, P55, P60, Tumor Necrosis Factor Receptor Superfamily, Member 1A, Tumor Necrosis Factor Binding Protein 1, Tumor Necrosis Factor Receptor Type 1, Tumor Necrosis Factor Receptor Type I, Tumor Necrosis Factor-Alpha Receptor, Tumor Necrosis Factor Receptor 1, CD120a Antigen, TNFR55, P55-R, TBP1, FPF
    Entrez ID:
    7132
    Related biomarkers:
    Expression
    Mutation
    over2years
    Genetic Variants in Double-Strand Break Repair Pathway Genes to Predict Platinum-Based Chemotherapy Prognosis in Patients With Lung Cancer. (PubMed, Front Pharmacol)
    Our study showed that variants in MAD2L2 rs746218 and TNFRSF1A rs4149570 were associated with shorter PFS or OS in patients with lung cancer who received platinum-based chemotherapy. These variants may be novel biomarkers for the prediction of prognosis of patients with lung cancer who receive platinum-based chemotherapy.
    Journal
    |
    TNFRSF1A (TNF Receptor Superfamily Member 1A) • MAD2L2 (Mitotic Arrest Deficient 2 Like 2)
    |
    TNFRSF1A rs4149570
    over2years
    TNFRSF1A Gene Polymorphism (-610 T > G, rs4149570) as a Predictor of Malnutrition and a Prognostic Factor in Patients Subjected to Intensity-Modulated Radiation Therapy Due to Head and Neck Cancer. (PubMed, Cancers (Basel))
    Moreover, the TT genotype of this gene was independently related to a higher risk of critical weight loss (CWL) (OR = 24.85; p = 0.0009). SNP (-610 T > G) of the TNFRSF1A may be a useful marker in the assessment of the risk of nutritional deficiencies in HNC patients treated with intensity-modulated radiotherapy (IMRT).
    Journal
    |
    TNFA (Tumor Necrosis Factor-Alpha) • TNFRSF1A (TNF Receptor Superfamily Member 1A)
    |
    TNFRSF1A rs4149570