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    BIOMARKER:

    TNFRSF14 overexpression

    i
    Other names: TNFRSF14, TNF Receptor Superfamily Member 14, HVEA, HVEM, TR2, Tumor Necrosis Factor Receptor Superfamily, Member 14 (Herpesvirus Entry Mediator), Tumor Necrosis Factor Receptor Superfamily Member 14, Herpes Virus Entry Mediator A, LIGHTR, CD270, ATAR, Tumor Necrosis Factor Receptor Superfamily, Member 14, Tumor Necrosis Factor Receptor-Like Gene2, Tumor Necrosis Factor Receptor-Like 2, Herpesvirus Entry Mediator A, Herpesvirus Entry Mediator, CD40-Like Protein, CD270 Antigen, HveA
    Entrez ID:
    8764
    Related biomarkers:
    Expression
    Mutation
    over1year
    T Cells Expressing CAR Equipped With Extracellular Domain of BTLA Are Effective Against HVEM-over-expressing Melanoma Cell Lines. (PubMed, Anticancer Res)
    HVEM-targeting CAR T cells may be useful for the treatment of melanoma.
    Preclinical • Journal
    |
    BTLA (B And T Lymphocyte Associated) • TNFRSF18 (TNF Receptor Superfamily Member 18)
    |
    TNFRSF14 overexpression
    over2years
    A bioinformatic analysis: the overexpression and clinical significance of HVEM in liver hepatocellular carcinoma (ITOC 2022)
    Conclusions In conclusion, our findings demonstrated high expression of HVEM in LIHC patients and is a potentially dangerous prognostic predictor of LIHC. We also found a correlation between HVEM immune-related signaling pathways and immune cell abundance, which may affect progression and prognosis of LIHC patients.
    Clinical
    |
    CD8 (cluster of differentiation 8) • AFP (Alpha-fetoprotein) • TNFRSF18 (TNF Receptor Superfamily Member 18)
    |
    TNFRSF14 overexpression