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    BIOMARKER:

    TLR7 overexpression

    i
    Other names: TLR7, Toll Like Receptor 7, Toll-Like Receptor 7, Toll-Like Receptor 7-Like, TLR7-Like, IMD74
    Entrez ID:
    51284
    almost2years
    Toll-like receptors 1-9 in small bowel neuroendocrine tumors-Clinical significance and prognosis. (PubMed, PLoS One)
    High TLR7 expression in SB-NET lymph node metastases was associated with worse prognosis. The current research has future perspective, as it can help create base for clinical drug trials to target specific TLRs with agonists or antagonists to treat neuroendocrine tumors.
    Journal • IO biomarker
    |
    TLR3 (Toll Like Receptor 3) • TLR5 (Toll Like Receptor 5) • TLR7 (Toll Like Receptor 7)
    |
    TLR7 overexpression
    3years
    Dissecting the role of toll-like receptor 7 in pancreatic cancer. (PubMed, Cancer Med)
    TLR7 may have opposing functions in tumor versus stroma cells. Further work is required to more precisely dissect the roles of TLR7 and its ligands in different populations of epithelial and stromal cells and to understand their relative contributions to tumor progression.
    Journal • IO biomarker
    |
    TLR7 (Toll Like Receptor 7)
    |
    TLR7 overexpression