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    BIOMARKER:

    TIMP2 overexpression

    i
    Other names: TIMP2, TIMP Metallopeptidase Inhibitor 2, CSC-21K, Tissue Inhibitor Of Metalloproteinases 2, Metalloproteinase Inhibitor 2, Tissue Inhibitor Of Metalloproteinase 2, Testicular Secretory Protein Li 57, TIMP-2, DDC8
    Entrez ID:
    7077
    Related biomarkers:
    Mutation
    12ms
    Chitosan hydrogel incorporated with bone marrow mesenchymal stem cell-derived exosomal TIMP2 to inhibit angiogenesis in cholangiocarcinoma. (PubMed, Tissue Cell)
    The study validates the therapeutic potential of BMSC-Exo/CS TIMP2 in CCA treatment. This innovative approach targets angiogenesis and Wnt/β-catenin signaling, providing a new avenue for more effective and comprehensive CCA therapies.
    Journal
    |
    MYC (V-myc avian myelocytomatosis viral oncogene homolog) • KDR (Kinase insert domain receptor) • CD9 (CD9 Molecule) • TIMP2 (TIMP Metallopeptidase Inhibitor 2) • TSG101 (Tumor Susceptibility 101)
    |
    TIMP2 overexpression
    over1year
    Long noncoding RNAs HAND2-AS1 ultrasound microbubbles suppress hepatocellular carcinoma progression by regulating the miR-873-5p/tissue inhibitor of matrix metalloproteinase-2 axis. (PubMed, World J Gastrointest Oncol)
    LncRNA HAND2-AS1 promotes TIMP2 expression by targeting miR-873-5p to inhibit HepG2 cell growth and delay HCC progression.
    Journal
    |
    MMP2 (Matrix metallopeptidase 2) • TIMP2 (TIMP Metallopeptidase Inhibitor 2) • MMP9 (Matrix metallopeptidase 9) • HAND2-AS1 (HAND2 Antisense RNA 1)
    |
    TIMP2 overexpression