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BIOMARKER:

TGFBI promoter hypermethylation

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Other names: TGFBI, Transforming Growth Factor Beta Induced, Transforming Growth Factor-Beta-Induced Protein Ig-H3, Transforming Growth Factor, Beta-Induced, 68kD, RGD-Containing Collagen-Associated Protein, Kerato-Epithelin, Beta Ig-H3, RGD-CAP, BIGH3, Transforming Growth Factor, Beta-Induced, 68kDa, Transforming Growth Factor Beta-Induced 68kDa, Betaig-H3, CDGG1, CDB1, CDG2, EBMD, CSD1, CSD2, CSD3, LCD1, CSD
Entrez ID:
almost6years
[VIRTUAL] TGFBI promoter methylation validation as an epigenetic biomarker for trastuzumab resistance in HER2+ breast cancer patients cohort (ESMO-BC-I 2020)
These preliminary results provide a basis for further studies to validate TGFBI hypermethylation as a potential epigenetic monitoring biomarker for trastuzumab resistance in HER2+ BC patients.Legal entity responsible for the study: University of Girona and Catalan Institute of Oncology (ICO), Dr. Josep Trueta Hospital. Funding: University of Girona.
Clinical
|
HER-2 (Human epidermal growth factor receptor 2) • TGFBI (Transforming Growth Factor Beta Induced)
|
HER-2 positive • TGFBI promoter hypermethylation
|
Herceptin (trastuzumab)
almost6years
[VIRTUAL] TGFBI promoter methylation validation as an epigenetic biomarker for trastuzumab resistance in HER2+ breast cancer patients cohort (ESMO-BC-I 2020)
These preliminary results provide a basis for further studies to validate TGFBI hypermethylation as a potential epigenetic monitoring biomarker for trastuzumab resistance in HER2+ BC patients.Legal entity responsible for the study: University of Girona and Catalan Institute of Oncology (ICO), Dr. Josep Trueta Hospital. Funding: University of Girona.
Clinical
|
HER-2 (Human epidermal growth factor receptor 2) • TGFBI (Transforming Growth Factor Beta Induced)
|
HER-2 positive • TGFBI promoter hypermethylation
|
Herceptin (trastuzumab)