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    BIOMARKER:

    TGFA overexpression

    i
    Other names: TFGA, Transforming Growth Factor Alpha, Protransforming Growth Factor Alpha, Transforming Growth Factor, Alpha, TGF-Alpha
    Entrez ID:
    7039
    Related biomarkers:
    Expression
    Associations

    News

    Trials
    over2years
    Phenotype screens of murine pancreatic cancer identify a Tgfa-Ccl2-paxillin axis driving human-like neural invasion. (PubMed, J Clin Invest)
    In human PDAC, phospho-paxillin and TGFa-expression constituted strong prognostic factors. Therefore, TGFa-CCL2-CCR4-p-paxillin axis is a clinically actionable target for constraining NI and tumor progression in PDAC.
    Preclinical • Journal • IO biomarker
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    CCR4 (C-C Motif Chemokine Receptor 4) • CCL2 (Chemokine (C-C motif) ligand 2) • PXN (Paxillin)
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    TGFA overexpression