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DRUG:

GDT002

i
Other names: GDT002, GDT-002, TEG002, autologous T cells transduced with a specific γδTCR, TEG 002
Associations
Company:
Century Therap
Drug class:
γδ TCR modulator
Associations
over1year
A Study to Investigate the Safety and Efficacy of TEG002 in Relapsed/Refractory Multiple Myeloma Patients (clinicaltrials.gov)
P1, N=26, Active, not recruiting, Gadeta B.V. | Recruiting --> Active, not recruiting
Enrollment closed
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IL6 (Interleukin 6)
|
GDT002
over2years
αβ-T Cells Engineered to Express γδ-T Cell Receptors Can Kill Neuroblastoma Organoids Independent of MHC-I Expression. (PubMed, J Pers Med)
Of note, efficacy of TEG002 treatment was superior to donor-matched untransduced αβ-T cells or endogenous γδ-T cells. Our data suggest that TEG002 may be a promising novel treatment option for a subset of neuroblastoma patients.
Journal • IO biomarker
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IFNG (Interferon, gamma)
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GDT002
almost3years
Clinical • Trial initiation date
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IL6 (Interleukin 6)
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GDT002
over3years
Clinical • Enrollment open
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IL6 (Interleukin 6)
|
GDT002
over3years
Clinical • New P1 trial
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IL6 (Interleukin 6)
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GDT002