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    BIOMARKER:

    T-cell-inflamed GEP signature

    2years
    Molecular analysis and favorable clinical outcomes in real-world patients with metastatic renal cell carcinoma. (PubMed, Acta Oncol)
    Data pointed at PD-L1 IHC and angiogenesis expression in ccRCC and hypoxia, glycolysis, and angiogenesis expression in nccRCC as potential prognostic factors. These findings may have implications for the design and interpretation of advanced RCC trials and to identify potential targets for combination therapy strategies.
    Clinical data • Journal • Real-world evidence • PD(L)-1 Biomarker • IO biomarker
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    PD-L1 (Programmed death ligand 1) • PD-L2 (Programmed Cell Death 1 Ligand 2)
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    PD-L1 expression • T-cell-inflamed GEP signature
    3years
    Prognostic significance of T-cell-inflamed gene expression profile and PD-L1 expression in patients with esophageal cancer. (PubMed, Cancer Med)
    Neither GEP nor PD-L1 expression was a prognostic marker in Asian and non-Asian patients with EC.
    Clinical • Journal • Gene Expression Profile • PD(L)-1 Biomarker • IO biomarker
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    PD-L1 (Programmed death ligand 1)
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    PD-L1 expression • T-cell-inflamed GEP signature