^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    BIOMARKER:

    STRA6 expression

    i
    Other names: STRA6, Signaling Receptor And Transporter Of Retinol STRA6, Stimulated By Retinoic Acid Gene 6 Protein Homolog, Retinol-Binding Protein Receptor STRA6, Retinol Binding Protein 4 Receptor, Receptor For Retinol Uptake STRA6, RBP Receptor, FLJ12541, Stimulated By Retinoic Acid Gene 6 Homolog (Mouse), Stimulated By Retinoic Acid Gene 6 Homolog, Stimulated By Retinoic Acid 6 Homolog, Stimulated By Retinoic Acid 6, MCOPCB8, PP14296, MCOPS9
    Entrez ID:
    64220
    8ms
    Identification of estrogen response-associated STRA6+ granulosa cells within high-grade serous ovarian carcinoma by single-cell sequencing. (PubMed, Heliyon)
    There is extreme heterogeneity of epithelial cells in HGSOC, and STRA6+ granulosa cells may be able to promote cancer progression. Our findings are benefit to the heterogeneity identification of HGSOC and develop targeted therapy strategy for HGSOC patients.
    Journal
    |
    AURKA (Aurora kinase A) • IRF1 (Interferon Regulatory Factor 1) • STRA6 (Signaling Receptor And Transporter Of Retinol STRA6)
    |
    IRF1 expression • STRA6 expression
    9ms
    ANLN Promotes the Proliferation and Migration of Gallbladder Cancer Cells via STRA6-Mediated Activation of PI3K/AKT Signaling. (PubMed, Cancers (Basel))
    We further confirmed that ANLN could upregulate STRA6 expression, which activated PI3K/AKT signaling to enhance the growth and movement of GBC cells. These findings demonstrate ANLN's involvement in GBC initiation and progression, suggesting its potential as a novel target for GBC.
    Journal
    |
    STRA6 (Signaling Receptor And Transporter Of Retinol STRA6) • ANLN (Anillin Actin Binding Protein)
    |
    STRA6 expression
    over1year
    STRA6 regulates tumor immune microenvironment and is a prognostic marker in BRAF-mutant papillary thyroid carcinoma. (PubMed, Front Endocrinol (Lausanne))
    Moreover, STRA6 promoted epithelial-mesenchymal transition via increased cancer-associated fibroblasts infiltration. Our study demonstrates STRA6 may serve as a prognostic marker for BRAF-mutated PTC, which may drive thyroid carcinogenesis via activation of oncogenic pathway and regulation of tumor immunosuppressive microenvironment.
    Journal
    |
    BRAF (B-raf proto-oncogene) • CD8 (cluster of differentiation 8) • STRA6 (Signaling Receptor And Transporter Of Retinol STRA6)
    |
    BRAF mutation • STRA6 expression