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    GENE:

    STMN3 (Stathmin 3)

    i
    Other names: STMN3, Stathmin 3, SCLIP, SCG10-Like Protein, Stathmin-Like 3, Stathmin-3
    Associations

    News

    Trials
    over1year
    Distinctive phenotypic and microenvironmental characteristics of neuroendocrine carcinoma and adenocarcinoma component in gastric mixed adenoneuroendocrine carcinoma. (PubMed, Mod Pathol)
    Although each component of MANEC shares the same genetic origin, distinctive phenotypes should not be overlooked when managing patients with MANEC. This study provides a useful validation dataset for future studies.
    Journal
    |
    COL1A1 (Collagen Type I Alpha 1 Chain) • MAP1B (Microtubule Associated Protein 1B) • STMN3 (Stathmin 3)
    over2years
    Identification and validation of a dysregulated TME-related gene signature for predicting prognosis, and immunological properties in bladder cancer. (PubMed, Front Immunol)
    Lastly, we identified SERPINB3 as significantly promoting BC cells migration and invasion through differential expression validation and in vitro phenotypic experiments. Our study developed a prognostic model based on nine TMRGs that accurately and stably predicted survival, guiding individual treatment for patients with BC, and providing new therapeutic strategies for the disease.
    Journal • Gene Signature • PD(L)-1 Biomarker • IO biomarker
    |
    CD8 (cluster of differentiation 8) • GZMA (Granzyme A) • SERPINB3 (Serpin family B member 3) • DPYSL2 (Dihydropyrimidinase Like 2) • STMN3 (Stathmin 3) • TMPRSS4 (Transmembrane Serine Protease 4)
    over2years
    Predicting Survival Signature of Bladder Cancer Related to Cancer-Associated Fibroblast (CAF) Constructed by Intersecting Genes in TCGA and GEO. (PubMed, Mol Biotechnol)
    Potential drugs targeted different CAF-related genes like vemurafenib, irofulven, ghiotepa, and idarubicin were found as well. We constructed a novel 9 CAF-related mRNAs prognostic model and explored the gene expression and potential functional information of related genes, which might be worthy of clinical application. In addition, potential chemotherapy drugs could provide useful insights into the potential clinical treatment of bladder cancer.
    Journal
    |
    GADD45B (Growth Arrest And DNA Damage Inducible Beta) • STMN3 (Stathmin 3)
    |
    Zelboraf (vemurafenib) • idarubicin hydrochloride • irofulven-1 (LP-100)