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    GENE:

    STK33 (Serine/Threonine Kinase 33)

    i
    Other names: STK33, Serine/Threonine Kinase 33, Serine/Threonine-Protein Kinase 33
    2years
    Serine/Threonine Kinase (STK) 33 promotes the proliferation and metastasis of human esophageal squamous cell carcinoma via inflammation-related pathway. (PubMed, Pathol Res Pract)
    Dysregulated STK33 signaling promotes ESCC growth and progression. Thus, our findings identified STK33 as a candidate treatment target that improves ESCC therapy.
    Journal
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    TGFB1 (Transforming Growth Factor Beta 1) • STK33 (Serine/Threonine Kinase 33)
    over4years
    NFYB potentiates STK33 activation to promote cisplatin resistance in diffuse large B-cell lymphoma. (PubMed, Leuk Res)
    The transcription factor NFYB expedites the transcription of SYK33 by binding to the STK33 promoter, thereby activating the Hedgehog signaling pathway in DLBCL cells, which in turn promotes the resistance of DLBCL cells to cisplatin.
    Journal
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    STK33 (Serine/Threonine Kinase 33)
    |
    cisplatin