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    BIOMARKER:

    ST6GAL1 elevation

    i
    Other names: ST6GAL1, ST6 Beta-Galactoside Alpha-2,6-Sialyltransferase 1, ST6Gal I, CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2,6-Sialyltransferase 1, ST6 N-Acetylgalactosaminide Alpha-2 6-Sialyltransferase 1, ST6 Beta-Galactosamide Alpha-2 6-Sialyltranferase 1, Beta-Galactoside Alpha-2,6-Sialyltransferase 1, B-Cell Antigen CD75, Alpha 2 6-ST 1, ST6GalI, SIAT1, CMP-N-Acetylneuraminate Beta-Galactosamide Alpha-2,6-Sialyltransferase, Sialyltransferase 1 (Beta-Galactoside Alpha-2,6-Sialyltransferase), Si
    Entrez ID:
    6480
    Related biomarkers:
    Others
    11ms
    ST6GAL1-Mediated Sialylation of PECAM-1 Promotes a Transcellular Diapedesis-Like Process that Directs Lung Tropism of Metastatic Breast Cancer. (PubMed, Cancer Res)
    Analysis of human breast cancer samples showed a correlation between elevated ST6GAL1/PECAM-1 expression and lung metastasis. These results suggest that targeting ST6GAL1-mediated α-2,6-sialylation could be a potential therapeutic strategy to prevent lung metastasis in breast cancer patients.
    Journal
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    CD31 (Platelet and endothelial cell adhesion molecule 1) • PECAM1 (Platelet And Endothelial Cell Adhesion Molecule 1) • ST6GAL1 (ST6 Beta-Galactoside Alpha-2,6-Sialyltransferase 1)
    |
    CD31 expression • ST6GAL1 elevation