^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    GENE:

    SRPRB (SRP Receptor Subunit Beta)

    i
    Other names: SRPRB, SRP Receptor Subunit Beta, SR-Beta, APMCF1, Signal Recognition Particle Receptor Subunit Beta, Signal Recognition Particle Receptor, B Subunit, Signal Recognition Particle Receptor, Beta Subunit, SRP Receptor Beta Subunit, Protein APMCF1
    6ms
    Expression of the genes QPRT, RAB26, and SRPRB in cancer tissue from patients with triple-negative breast cancer as a biomarker for diagnosis, pharmacotherapy strategy, and survival: Evidence from bioinformatic database analysis. (PubMed, Int J Clin Pharmacol Ther)
    QPRT, RAB26, and SRPRB may be three potential novel prognostic biomarkers for TNBC and will provide potential guidance value for future research on TNBC.
    Journal
    |
    RAS (Rat Sarcoma Virus) • QPRT (Quinolinate Phosphoribosyltransferase) • SRPRB (SRP Receptor Subunit Beta)
    2years
    Selenomethionine Suppress the Progression of Poorly Differentiated Thyroid Cancer via LncRNA NONMMUT014201/miR-6963-5p/Srprb Pathway. (PubMed, Comb Chem High Throughput Screen)
    Collectively, SeMet inhibits the growth of PDTC in a dose-dependent manner through LncRNA NONMMUT014201/miR-6963-5p/Srprb signal pathway, thus suggesting that SeMet might be a potential drug for PDTC treatment.
    Journal • IO biomarker
    |
    BCL2 (B-cell CLL/lymphoma 2) • MMP2 (Matrix metallopeptidase 2) • CASP3 (Caspase 3) • MMP9 (Matrix metallopeptidase 9) • PCNA (Proliferating cell nuclear antigen) • SRPRB (SRP Receptor Subunit Beta)
    |
    BCL2 expression • SRPRB overexpression • PCNA expression
    |
    selenomethionine (SLM)
    over2years
    Integration of scRNA-seq and bulk RNA-seq constructs a stemness-related signature for predicting prognosis and immunotherapy responses in hepatocellular carcinoma. (PubMed, J Cancer Res Clin Oncol)
    The novel stemness-related prognostic model is a promising biomarker for estimating overall survival in HCC.
    Journal • IO biomarker
    |
    LDHA (Lactate dehydrogenase A) • YBX1 (Y-Box Binding Protein 1) • CDC20 (Cell Division Cycle 20) • CLEC3B (C-Type Lectin Domain Family 3 Member B) • SRPRB (SRP Receptor Subunit Beta)
    over2years
    Immunogenic landscape and risk score prediction based on unfolded protein response (UPR)-related molecular subtypes in hepatocellular carcinoma. (PubMed, Front Immunol)
    Moreover, ATF4 was upregulated, while GOSR2, PDIA6 and SRPRB were downregulated in sorafenib-treated HCC cells. The UPR-related prognostic signature containing four URGs exhibits high potential application value and performs well in the evaluation of effects of chemotherapy/immunotherapy and clinical prognosis.
    Journal • IO biomarker
    |
    ATF4 (Activating Transcription Factor 4) • GOSR2 (Golgi SNAP Receptor Complex Member 2) • PDIA6 (Protein Disulfide Isomerase Family A Member 6) • SRPRB (SRP Receptor Subunit Beta)
    |
    sorafenib