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    BIOMARKER:

    SRC amplification

    i
    Other names: SRC, SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase, V-Src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog, Proto-Oncogene Tyrosine-Protein Kinase Src, Proto-Oncogene C-Src, P60-Src, SRC1, Protooncogene SRC, Rous Sarcoma, Tyrosine-Protein Kinase SRC-1, Tyrosine Kinase Pp60c-Src, Pp60c-Src, C-SRC, THC6, ASV
    Entrez ID:
    6714
    Related biomarkers:
    Expression
    Mutation
    Others
    over2years
    Biomarker concordance between matched primary and metastatic colorectal tumors (AACR 2022)
    Our results demonstrates high concordance across multiple biomarkers between the primary and paired metastatic colorectal tumors. Molecular features of ovarian metastasis is more prone to inconsistent with primary sites than liver metastasis, which remains to be further verified in a large population.
    Tumor Mutational Burden • BRCA Biomarker
    |
    EGFR (Epidermal growth factor receptor) • KRAS (KRAS proto-oncogene GTPase) • BRAF (B-raf proto-oncogene) • TMB (Tumor Mutational Burden) • NRAS (Neuroblastoma RAS viral oncogene homolog) • BRCA2 (Breast cancer 2, early onset) • ACVR2A (Activin A Receptor Type 2A) • MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4)
    |
    KRAS mutation • EGFR mutation • NRAS mutation • EGFR amplification • SRC amplification