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    BIOMARKER:

    SPP1 mutation

    i
    Other names: SPP-1, BSPI, Secreted Phosphoprotein 1, Osteopontin, Early T-Lymphocyte Activation 1, Urinary Stone Protein, Nephropontin, Uropontin, BNSP, OPN, Secreted Phosphoprotein 1 (Osteopontin, Bone Sialoprotein I, Early T-Lymphocyte Activation 1), Osteopontin/Immunoglobulin Alpha 1 Heavy Chain Constant Region Fusion Protein, Secreted Phosphoprotein 1 Variant 6, SPP1/CALPHA1 Fusion, Bone Sialoprotein 1, Bone Sialoprotein I, ETA-1
    Entrez ID:
    6696
    Related biomarkers:
    Others
    3years
    The role of SPP1 as a prognostic biomarker and therapeutic target in head and neck squamous cell carcinoma. (PubMed, Int J Oral Maxillofac Surg)
    Furthermore, SPP1 expression levels in HNSCC were positively correlated with the infiltration of CD4 cells, macrophages, neutrophils, and dendritic cells. The study results suggest that SPP1 may represent a diagnostic and prognostic biomarker, as well as a potential therapeutic target in HNSCC.
    Journal
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    SPP1 (Secreted Phosphoprotein 1) • CD4 (CD4 Molecule)
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    SPP1 mutation