^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    BIOMARKER:

    SPINK2 overexpression

    i
    Other names: SPINK2, Serine Peptidase Inhibitor Kazal Type 2, HUSI-II, Serine Protease Inhibitor Kazal-Type 2, Epididymis Tissue Protein Li 172, Acrosin-Trypsin Inhibitor, Serine Peptidase Inhibitor, Kazal Type 2 (Acrosin-Trypsin Inhibitor), Serine Protease Inhibitor, Kazal Type 2 (Acrosin-Trypsin Inhibitor), SPGF29
    Entrez ID:
    6691
    almost2years
    RARRES1 inhibits hepatocellular carcinoma progression and increases its sensitivity to lenvatinib through interaction with SPINK2. (PubMed, Biol Direct)
    Our findings highlighted that RARRES1 can inhibit HCC progression and regulate HCC sensitivity to lenvatinib by interacting SPINK2, representing a new tumor suppressor RARRES1/SPINK2 axis in HCC that modulates sensitivity to lenvatinib.
    Journal
    |
    SPINK2 (Serine Peptidase Inhibitor Kazal Type 2)
    |
    SPINK2 overexpression
    |
    Lenvima (lenvatinib)