The results indicate that MPP5, SNX7, LSM12, and GALNT3 are significantly associated with radiotherapy sensitivity in CC cells. A prognostic risk model based on these genes demonstrated strong predictive capabilities for patient outcomes in radiotherapy, suggesting these genes as effective predictors and potential therapeutic targets for treating CC.
Our results highlight the importance of mitophagy dysregulation in the pathogenesis of glioblastoma and identify SNX7 as a novel therapeutic target. Further research is needed to elucidate the underlying mechanisms of SNX7 in glioblastoma and validate its clinical significance. These findings may facilitate the development of personalized treatment strategies and improve outcomes for glioblastoma patients.