SNORD138 (Small Nucleolar RNA, C/D Box 138)

News alerts, weekly reports and conference planners

1year

LncRNA U731166 Increases the Accumulation of TGFBR1 by Sponging miR-3607-3p in Esophageal Squamous-Cell Carcinomas (ESCC) to Promote Tumor Metastasis. (PubMed, Iran J Biotechnol)

U731166 and miR-3607-3p were closely associated with patients' tumor metastasis but not tumor size. U731166 may upregulate TGFBR1 by sponging miR-3607-3p in ESCC cells to promote tumor metastasis.

1 year ago

Journal

SNORD138 (Small Nucleolar RNA, C/D Box 138) • TGFBR1 (Transforming Growth Factor Beta Receptor 1)

over3years

Prognostic MicroRNA Panel for HCV-Associated HCC: Integrating Computational Biology and Clinical Validation. (PubMed, Cancers (Basel))

These preliminary data show that the novel miRNAs panel (miR-150, miR-199a, miR-224, miR-424, and miR-3607) could serve as a potential non-invasive biomarker for HCC early prediction in chronic HCV patients. Further prospective studies on a larger cohort of patients should be conducted to assess the potential prognostic ability of the miRNAs panel.

over 3 years ago

Journal

AFP (Alpha-fetoprotein) • MIR142 (MicroRNA 142) • MIR199A (MicroRNA 199a) • MIR424 (MicroRNA 424) • MIR150 (MicroRNA 150) • MIR183 (MicroRNA 183) • MIR215 (MicroRNA 215) • MIR217 (MicroRNA 217) • MIR224 (MicroRNA 224) • SNORD138 (Small Nucleolar RNA, C/D Box 138)

5years

XIAP, commonly targeted by tumor suppressive miR-3607-5p and miR-3607-3p, promotes proliferation and inhibits apoptosis in hepatocellular carcinoma. (PubMed, Genomics)

Finally, a XIAP-associated protein-protein interaction network, consisting of 10 positively correlated genes, was established. Collectively, we for the first time suggest that miR-3607-3p and miR-3607-5p inhibit HCC by acting one common target XIAP.

5 years ago

Journal

XIAP (X-Linked Inhibitor Of Apoptosis) • SNORD138 (Small Nucleolar RNA, C/D Box 138)