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    BIOMARKER:

    SKI overexpression

    i
    Other names: SKI, SKI Proto-Oncogene, V-Ski Avian Sarcoma Viral Oncogene Homolog, Proto-Oncogene C-Ski, Ski Oncogene, Ski Oncoprotein
    Entrez ID:
    6497
    Related biomarkers:
    Others
    Associations

    News

    Trials
    2years
    Suppression of intrahepatic cholangiocarcinoma cell growth by SKI via upregulation of the CDK inhibitor p21. (PubMed, FEBS Open Bio)
    These data indicate SKI involvement in p21 transcription and that SKI-p21 signaling causes cell cycle arrest in G1, suppressing intrahepatic CC cell growth. Therefore, SKI may be a potential therapeutic target for intrahepatic CC.
    Journal
    |
    SKI (SKI Proto-Oncogene)
    |
    SKI overexpression
    almost3years
    MicroRNA-195-5p inhibits the progression of hemangioma via targeting SKI. (PubMed, Exp Ther Med)
    Collectively, the results of the present study demonstrated that miR-195-5p suppressed HA progression and its effects were mediated via SKI. Therefore, the miR-195-5p/SKI axis may represent a novel therapeutic target for HA.
    Journal • IO biomarker
    |
    BCL2 (B-cell CLL/lymphoma 2) • PARP1 (Poly(ADP-Ribose) Polymerase 1) • BAX (BCL2-associated X protein) • SKI (SKI Proto-Oncogene) • MIR195 (MicroRNA 195)
    |
    BCL2 expression • BAX expression • SKI overexpression