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DRUG:

SJ-C1044

i
Other names: SJ-C1044
Company:
Samjin Pharma
Drug class:
pan-RAF inhibitor, Angiogenesis inhibitor
over1year
Targeting RAF Isoforms and Tumor Microenvironments in RAS or BRAF Mutant Colorectal Cancers with SJ-C1044 for Anti-Tumor Activity. (PubMed, Curr Issues Mol Biol)
Thus, SJ-C1044 shows immunomodulatory potential and the ability to enhance antitumor responses. The study underscores the therapeutic potential of SJ-C1044 as a novel pan-RAF inhibitor capable of targeting oncogenic signaling pathways and overcoming immune suppression in CRC.
Journal
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KRAS (KRAS proto-oncogene GTPase) • BRAF (B-raf proto-oncogene) • KDR (Kinase insert domain receptor) • RAS (Rat Sarcoma Virus) • CSF1R (Colony stimulating factor 1 receptor)
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KRAS mutation • BRAF mutation • RAS mutation
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SJ-C1044