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    BIOMARKER:

    SGK1 overexpression

    i
    Other names: SGK1, Serum/Glucocorticoid Regulated Kinase 1, Serine/Threonine-Protein Kinase Sgk1, SGK, Serum/Glucocorticoid-Regulated Kinase 1, Serum/Glucocorticoid Regulated Kinase, Serine/Threonine Protein Kinase SGK, Sgk1 Variant I3
    Entrez ID:
    6446
    Related biomarkers:
    Others
    3years
    The Serum- and Glucocorticoid-Inducible Kinase 1 (SGK1) as a Novel Therapeutic Target in Mantle Cell Lymphoma. (PubMed, Cancer Control)
    SGK1 may be a novel candidate therapeutic target and simultaneous inhibition of SGK1 and BTK may be a promising therapeutic strategy for MCL patients. Further pre-clinical and even clinical studies of SGK1 inhibitor or combination with BTK inhibitor are essential.
    Journal
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    JAK2 (Janus kinase 2)
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    SGK1 overexpression