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    BIOMARKER:

    SF3B1 K666E

    i
    Other names: SF3B1, Splicing Factor 3b Subunit 1, Splicing Factor 3b Subunit 1 155kDa, Spliceosome-Associated Protein 155, Splicing Factor 3B Subunit 1, SF3b155, SAP155, Pre-MRNA Splicing Factor SF3b 155 KDa Subunit, Pre-MRNA-Splicing Factor SF3b 155 KDa Subunit, Splicing Factor 3b Subunit 1 155kD, Pre-MRNA Processing 10, SAP 155, Hsh155, PRPF10, PRP10, MDS
    Entrez ID:
    23451
    Related biomarkers:
    Mutation
    Others
    almost2years
    Prognostic correlation of NOTCH1 and SF3B1 mutations with chromosomal abnormalities in chronic lymphocytic leukemia patients. (PubMed, Cancer Rep (Hoboken))
    The correlation of NOTCH1 and SF3B1 mutations with chromosomal abnormalities and CD38 expression may reveal the overall patient's survival rate. The mutations may be effective in the clonal expansion and progression of CLL, particularly in the diagnosis stage, as well as the control and management of the treatment.
    Journal • IO biomarker
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    NOTCH1 (Notch 1) • SF3B1 (Splicing Factor 3b Subunit 1) • CD38 (CD38 Molecule)
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    NOTCH1 mutation • Chr del(11q) • SF3B1 mutation • CD38 expression • CD38 positive • NOTCH1 expression • Chr del(13)(q14) • SF3B1 K666E