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    BIOMARKER:

    SESN2 overexpression

    i
    Other names: SESN2, Sestrin 2, Sestrin-2, SEST2, Hypoxia Induced Gene 95, Hypoxia-Induced Gene, Hypoxia-Induced, HI95, SES2
    Entrez ID:
    83667
    almost2years
    Sestrin 2 protects human lens epithelial cells from oxidative stress and apoptosis induced by hydrogen peroxide by regulating the mTOR/Nrf2 pathway. (PubMed, Int J Immunopathol Pharmacol)
    SESN2 protected HLECs damage induced by H2O2, which was related to the activation of mTOR/Nrf2 pathway.
    Journal • IO biomarker
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    BCL2 (B-cell CLL/lymphoma 2) • TNFA (Tumor Necrosis Factor-Alpha) • IL18 (Interleukin 18) • RPS6KB1 (Ribosomal Protein S6 Kinase B1) • IL1B (Interleukin 1, beta) • SESN2 (Sestrin 2) • CAT (Catalase)
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    SESN2 overexpression
    |
    sirolimus