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    BIOMARKER:

    SERPINH1 overexpression

    i
    Other names: SERPINH1, Serpin family H member 1, Serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), Cell proliferation-inducing gene 14 protein, SERPINH2 , AsTP3, HSP47, Colligin-1, Colligin-2, Rheumatoid arthritis antigen A-47
    Entrez ID:
    871
    6ms
    SERPINH1 enhances the malignancy of osteosarcoma via PI3K-Akt signaling pathway. (PubMed, Transl Oncol)
    SERPINH1 partakes in the biological process of osteosarcoma as a tumor promotor and may be an emerging biomarker in osteosarcoma.
    Journal
    |
    SERPINH1 (Serpin family H member 1)
    |
    SERPINH1 overexpression
    over1year
    High SERPINH1 expression predicts poor prognosis in lung adenocarcinoma. (PubMed, J Thorac Dis)
    Using LUAD tissues and clinical samples, we showed that SERPINH1 can be used as a prognostic biomarker for LUAD. Our findings provide a new approach and strategy for the clinical treatment of LUAD patients.
    Journal • Tumor mutational burden • IO biomarker
    |
    TMB (Tumor Mutational Burden) • SERPINH1 (Serpin family H member 1)
    |
    TMB-H • TMB-L • SERPINH1 overexpression