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    GENE:

    SDK1 (Sidekick Cell Adhesion Molecule 1)

    i
    Other names: SDK1, Sidekick Cell Adhesion Molecule 1, Protein Sidekick-1, FLJ31425, Sidekick Homolog 1, Cell Adhesion Molecule (Chicken), Sidekick Homolog 1, Cell Adhesion Molecule, Sidekick Homolog 1 (Chicken)
    over1year
    Characterisation of cells markers associated with IKZF1plus in BCP-ALL. (PubMed, Transl Oncol)
    In this scenario, we found associations between IKZF1plus and certain genes in BCP-ALL, being KCNA5 and GREB1 the most promising biomarkers for predicting IKZF1plus. A deeper understanding of these genetic profiles will allow a better risk assessment and offer precise rationale for therapeutic strategies in BCP-ALL.
    Journal
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    CDKN2A (Cyclin Dependent Kinase Inhibitor 2A) • IKZF1 (IKAROS Family Zinc Finger 1) • CDKN2B (Cyclin Dependent Kinase Inhibitor 2B) • PAX5 (Paired Box 5) • CD200 (CD200 Molecule) • BTLA (B And T Lymphocyte Associated) • SDK1 (Sidekick Cell Adhesion Molecule 1) • VPREB1 (V-Set Pre-B Cell Surrogate Light Chain 1)
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    CDKN2A deletion • IKZF1 deletion • VPREB1 deletion
    over1year
    Genome-wide discovery of selection signatures in four Anatolian sheep breeds revealed by ddRADseq. (PubMed, Sci Rep)
    The results of this study imply that GKR may become genetically different from the AKR breed at the genome level due to most probably experiencing different adaptation processes occurring in raised climatic conditions. These differences should be conserved to face future challenges, while other native Turkish sheep breeds could be monitored via genome-wide high-density SNP data to obtain deeper knowledge about the effects of natural selection.
    Journal
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    SDK1 (Sidekick Cell Adhesion Molecule 1)
    almost2years
    Differentially expressed genes associated with high metabolic tumor volume served as diagnostic markers and potential therapeutic targets for pancreatic cancer. (PubMed, J Transl Med)
    MAGs may serve as diagnostic markers and miRNA therapeutic targets for pancreatic cancer. Among the MAGs, KIF11, RCC1, ADCY, and SDK1 may be early diagnostic markers.
    Journal
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    KIF11 (Kinesin Family Member 11) • SDK1 (Sidekick Cell Adhesion Molecule 1)
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    KIF11 overexpression
    over3years
    Exploring the potential mechanism of emetine against coronavirus disease 2019 combined with lung adenocarcinoma: bioinformatics and molecular simulation analyses. (PubMed, BMC Cancer)
    This study found that emetine may inhibit the entry and replication of SARS-CoV-2 and enhance tumor immunity by bounding to DDP4 and Mpro.
    Journal
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    LDHA (Lactate dehydrogenase A) • IL6 (Interleukin 6) • CCL20 (C-C Motif Chemokine Ligand 20) • PRF1 (Perforin 1) • SDK1 (Sidekick Cell Adhesion Molecule 1) • SLC6A4 (Solute Carrier Family 6 Member 4)
    over3years
    Differential expression and analysis of extrachromosomal circular DNAs as serum biomarkers in lung adenocarcinoma. (PubMed, J Clin Lab Anal)
    Our study first showed that several eccDNAs were aberrantly expressed in LAD, among which CircD-PDZRN3 and CircD-LGR6 clearly distinguished LAD patients from healthy controls, indicating their potential as biomarkers.
    Journal
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    CEACAM5 (CEA Cell Adhesion Molecule 5) • KRT19 (Keratin 19) • SDK1 (Sidekick Cell Adhesion Molecule 1) • SLC16A3 (Solute Carrier Family 16 Member 3) • UMODL1 (Uromodulin Like 1)