^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    GENE:

    SCHIP1 (Schwannomin Interacting Protein 1)

    i
    Other names: SCHIP1, Schwannomin Interacting Protein 1, SCHIP-1, Schwannomin-Interacting Protein 1, Schwannomin Interacting Protein 1 Variant 2, Schwannomin Interacting Protein 1 Variant 1
    Associations

    News

    Trials
    2ms
    Analysis of Hepatitis B Virus Integration Reveals New Insights of Oncogenic Mechanism in Dysplastic Liver Nodule. (PubMed, J Med Virol)
    Moreover, clinical indicators revealed significant prolongation of prothrombin time in two DN patients with HBV integrations in SCHIP1 and ZDHHC14. As a new insight regarding HBV integrations in DN stage, our findings suggest a possible role of HBV integration in the transformation of DN to early-stage liver cancer by affecting the expression of key genes.
    Journal
    |
    SCHIP1 (Schwannomin Interacting Protein 1) • YPEL2 (Yippee Like 2)
    2ms
    Analysis of HBV Integration Reveals New Insights of Oncogenic Mechanism in Dysplastic Liver Nodule. (PubMed, J Med Virol)
    Moreover, clinical indicators revealed significant prolongation of prothrombin time in two DN patients with HBV integrations in SCHIP1 and ZDHHC14. As a new insight regarding HBV integrations in DN stage, our findings suggest a possible role of HBV integration in the transformation of DN to early-stage liver cancer by affecting the expression of key genes.
    Journal
    |
    SCHIP1 (Schwannomin Interacting Protein 1) • YPEL2 (Yippee Like 2)
    over2years
    TGM2, HMGA2, FXYD3, and LGALS4 genes as biomarkers in acquired oxaliplatin resistance of human colorectal cancer: A systems biology approach. (PubMed, PLoS One)
    The results indicated the up-regulation of TGM2 and HMGA2 in HCT116/OX-R10 cells with high OX-RI and down-regulation of FXYD3, LGALS4, and ECI2 in both cell types. Based on the results, TGM2, HMGA2, FXYD3, and LGALS4 genes are related to oxaliplatin-resistant CRC and may serve as novel therapeutic targets.
    Journal
    |
    PDZK1IP1 (PDZK1 interacting protein 1) • CD33 (CD33 Molecule) • MAGEA4 (Melanoma antigen family A, 4) • TGM2 (Transglutaminase 2) • ALDH2 (Aldehyde Dehydrogenase 2 Family Member) • CEACAM6 (CEA Cell Adhesion Molecule 6) • HMGA2 (High mobility group AT-hook 2) • QPRT (Quinolinate Phosphoribosyltransferase) • FXYD3 (FXYD Domain Containing Ion Transport Regulator 3) • LGALS4 (Galectin 4) • VSNL1 (Visinin Like 1) • AKAP12 (A-Kinase Anchoring Protein 12) • ALDH3A1 (Aldehyde Dehydrogenase 3 Family Member A1) • MAGEA6 (MAGE Family Member A6) • SCHIP1 (Schwannomin Interacting Protein 1)
    |
    oxaliplatin
    3years
    A transient receptor potential channel-related model based on machine learning for evaluating tumor microenvironment and immunotherapeutic strategies in acute myeloid leukemia. (PubMed, Front Immunol)
    Finally, it was found that SCHIP1 may be the oncogenic gene. The results of this study will help in understanding the role of TRP and SCHIP1 in the prognosis and development of AML.
    Journal • IO biomarker • Machine learning
    |
    IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2) • DNMT3A (DNA methyltransferase 1) • MUC16 (Mucin 16, Cell Surface Associated) • SCHIP1 (Schwannomin Interacting Protein 1)
    |
    IDH2 mutation • DNMT3A mutation • MUC16 mutation
    over3years
    The Potential of Extracellular Vesicle Derived microRNAs As a Biomarker in Acute Myeloid Leukemia (ASH 2022)
    Conclusion Overall, the findings of this study revealed that EV-derived miRNAs may serve as biomarkers for risk stratification and prognosis in AML. However, further studies are required to validate these EV-derived miRNAs in other cohorts before their implementation in clinical practice.
    ADAMTS3 (ADAM Metallopeptidase With Thrombospondin Type 1 Motif 3) • MIR143 (MicroRNA 143) • CALCRL (Calcitonin Receptor Like Receptor) • DDIT4 (DNA Damage Inducible Transcript 4) • MIR181B1 (MicroRNA 181b-1) • SCHIP1 (Schwannomin Interacting Protein 1)