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    GENE:

    SAP30L (SAP30 Like)

    i
    Other names: SAP30L, SAP30 Like, NS4ATP2, HCV Non-Structural Protein 4A-Transactivated Protein 2, Histone Deacetylase Complex Subunit SAP30L, Sin3 Corepressor Complex Subunit SAP30L, Sin3-Associated Protein P30-Like, FLJ11526, Sin3A Associated Protein P30-Like
    Associations

    News

    Trials
    3ms
    Development and validation of a novel signature to predict the survival and affect the immune microenvironment of esophageal squamous cell carcinoma: epigenetic-related genes. (PubMed, Front Immunol)
    Drug sensitivity analysis identified four promising therapeutic compounds-PD-0325901, Bryostatin-1, ATRA, and Roscovitine-with potential clinical utility for ESCC treatment. The findings of this study offer clinically relevant insights for prognostic stratification and characterization of the immune microenvironment in ESCC patients. Moreover, these results provide novel perspectives that may contribute to the development of more effective prognostic tools and targeted therapeutic strategies for ESCC management.
    Journal • IO biomarker
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    CD8 (cluster of differentiation 8) • IDO1 (Indoleamine 2,3-dioxygenase 1) • CHEK1 (Checkpoint kinase 1) • NCOR1 (Nuclear Receptor Corepressor 1) • BMI1 (BMI1 proto-oncogene, polycomb ring finger) • SATB1 (SATB Homeobox 1) • BUB1 (BUB1 Mitotic Checkpoint Serine/Threonine Kinase) • GSE1 (Gse1 Coiled-Coil Protein) • SSRP1 (Structure Specific Recognition Protein 1) • SAP30L (SAP30 Like)
    |
    Gomekli (mirdametinib) • seliciclib (CYC202)
    over2years
    Invasive Breast Cancer: miR-24-2 Targets Genes Associated with Survival and Sensitizes MDA-MB-231 Cells to Berberine. (PubMed, OMICS)
    In all, this study reports on the novel target genes of miR-24-2 in invasive breast cancer/TNBC, and that miR-24-2 sensitizes MDA-MB-231 cells to berberine. These data lend evidence for the translational potentials of miR-24-2 for invasive breast cancer diagnostic and therapeutic innovation.
    Journal • BRCA Biomarker
    |
    BRCA (Breast cancer early onset) • HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ Beta 1) • IL1R1 (Interleukin 1 receptor, type I) • L1CAM (L1 cell adhesion molecule) • MIR24-2 (MicroRNA 24-2) • RACGAP1 (Rac GTPase activating protein 1) • SOD2 (Superoxide Dismutase 2) • DTX4 (Deltex E3 Ubiquitin Ligase 4) • HLA-DQB2 (Major Histocompatibility Complex, Class II, DQ Beta 2) • LYRM7 (LYR Motif Containing 7) • SAP30L (SAP30 Like) • SLC1A3 (Solute Carrier Family 1 Member 3) • TIMM17A (Translocase Of Inner Mitochondrial Membrane 17A)