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    BIOMARKER:

    RPTOR mutation

    i
    Other names: RPTOR, Regulatory Associated Protein Of MTOR Complex 1, Raptor, KIAA1303, KOG1, Mip1, Regulatory-Associated Protein Of MTOR, P150 Target Of Rapamycin (TOR)-Scaffold Protein Containing WD-Repeats, Regulatory Associated Protein Of MTOR, Complex 1, P150 Target Of Rapamycin (TOR)-Scaffold Protein, Regulatory Associated Protein Of MTOR, RAPTOR
    Entrez ID:
    57521
    2years
    RPTOR mutation: a novel predictor of efficacious immunotherapy in melanoma. (PubMed, Invest New Drugs)
    RPTOR-Mut melanoma patients had higher expression levels of immune-related genes than the RPTOR-WT patients. Our results suggest that RPTOR mutation could serve as a predictor of effective immunotherapy for melanoma.
    Journal • Tumor mutational burden • IO biomarker
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    TMB (Tumor Mutational Burden) • CD4 (CD4 Molecule) • RPTOR (Regulatory Associated Protein Of MTOR Complex 1)
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    TMB-H • RPTOR mutation