Combination therapy • Clinical • PD(L)-1 Biomarker • IO biomarker
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PD-L1 (Programmed death ligand 1) • CD8 (cluster of differentiation 8) • TIGIT (T Cell Immunoreceptor With Ig And ITIM Domains 2) • CXCL9 (Chemokine (C-X-C motif) ligand 9) • CD27 (CD27 Molecule) • CSF2 (Colony stimulating factor 2) • TRB (T Cell Receptor Beta Locus)
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PD-L1 expression • CSF2 expression • PD-L1 expression + CD8 positive
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PD-L1 IHC 28-8 pharmDx • nCounter® PanCancer IO 360™ Panel
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Opdivo (nivolumab) • Yervoy (ipilimumab) • vusolimogene oderparepvec (RP1)