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GENE:

ROPN1B (Rhophilin Associated Tail Protein 1B)

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Other names: ROPN1B, Rhophilin Associated Tail Protein 1B, Ropporin, Rhophilin Associated Protein 1B, Rhophilin-Associated Protein 1B, Ropporin-1B, Testis Tissue Sperm-Binding Protein Li 83P, AKAP-Binding Sperm Protein Ropporin
Associations
Trials
almost3years
A genome-wide association study identifies the association of common variants in the major histocompatibility complex with cervical cancer in black South African women (AACR 2023)
The genes in these loci are implicated in numerous pathways including antiviral immunity, DNA repair, the regulation of p53, apoptosis, cell growth and differentiation. These discoveries demonstrate the important contribution of common genetic variants to cervical cancer susceptibility and provide insights into its pathogenesis in women of African ancestry.
Clinical
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HLA-DRA (Major Histocompatibility Complex, Class II, DR Alpha) • HLA-C (Major Histocompatibility Complex, Class I, C) • ROPN1B (Rhophilin Associated Tail Protein 1B) • TRIM31 (Tripartite Motif Containing 31)