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    BIOMARKER:

    RIPK3 underexpression

    i
    Other names: RIPK3, Receptor Interacting Serine/Threonine Kinase 3, RIP3, Receptor-Interacting Serine/Threonine-Protein Kinase 3, RIP-Like Protein Kinase 3, RIP-3, Receptor-Interacting Serine-Threonine Kinase 3, Receptor Interacting Protein 3, Receptor-Interacting Protein 3
    Entrez ID:
    11035
    almost5years
    Clinical Significance of Receptor-Interacting Protein 3 and Parkin, Essential Molecules for Necroptosis, in Breast Cancer. (PubMed, J Breast Cancer)
    Low RIP3 and high Parkin expression are associated with aggressive clinical features in breast cancer. RIP3, a molecular marker of necroptosis, is an independent factor associated with survival in breast cancer. Further in-depth studies are needed to investigate the role of necroptosis in breast cancer development, metastasis, and treatment in the future.
    Clinical • Journal
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    HER-2 (Human epidermal growth factor receptor 2) • PGR (Progesterone receptor) • RIPK1 (Receptor Interacting Serine/Threonine Kinase 1) • RIPK3 (Receptor Interacting Serine/Threonine Kinase 3)
    |
    EGFR positive • RIPK3 underexpression