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    DRUG:

    RG6440

    i
    Other names: RG6440, SOF10, RO7496353, RG 6440, RO 7496353, SOF 10, RG-6440, RO-7496353, SOF-10
    Associations

    News

    Trials
    Company:
    Roche
    Drug class:
    TGF-β1 inhibitor
    Related drugs:
    Associations

    News

    Trials
    over1year
    A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of-Care Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors (clinicaltrials.gov)
    P1, N=120, Not yet recruiting, Genentech, Inc.
    New P1 trial • Combination therapy • Checkpoint inhibition • Metastases
    |
    Opdivo (nivolumab) • Tecentriq (atezolizumab) • gemcitabine • capecitabine • albumin-bound paclitaxel • oxaliplatin • Teysuno (gimeracil/oteracil/tegafur) • RG6440