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    GENE:

    RAET1L (Retinoic Acid Early Transcript 1L)

    i
    Other names: RAET1L, Retinoic Acid Early Transcript 1L, Retinoic Acid Early Transcript 1L Protein, UL16-Binding Protein 6, ULBP6, UL16 Binding Protein 6
    Associations

    News

    Trials
    11ms
    23ME-01473, an Fc Effector-Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell-Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation. (PubMed, Cancer Res Commun)
    We identify ULBP6 as a potential keystone member of the NKG2D pathway, which is important for antitumor immunity. Targeting ULBP6 may hold therapeutic promise for patients with cancer.
    Journal
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    NKG2D (killer cell lectin like receptor K1) • RAET1L (Retinoic Acid Early Transcript 1L)
    over3years
    Comprehensive Analysis of a Novel Immune-Related Gene Signature in Lung Adenocarcinoma. (PubMed, J Clin Med)
    The prognostic risk model was also significantly associated with the infiltration of immune cells in LUAD microenvironments. To sum up, a novel immune-related six-gene signature (CR2, FGF5, INSL4, RAET1L, AGER, and TNFRSF13C) was identified that could predict LUAD survival and is highly related to B cells and dendritic cells, which may provide a theoretical basis of personalized treatment for targeted immunotherapy.
    Journal • Gene Signature • IO biomarker
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    TNFRSF13C (TNF Receptor Superfamily Member 13C) • RAET1L (Retinoic Acid Early Transcript 1L)