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    BIOMARKER:

    RAD51B promoter methylation + PD-L1 expression

    i
    Other names: RAD51B, RAD51 Paralog B, DNA Repair Protein RAD51 Homolog 2, RAD51 Homolog B, RAD51L1, R51H2, RAD51 Homolog B (S. Cerevisiae), RAD51 (S. Cerevisiae)-Like 1, RAD51-Like 1 (S. Cerevisiae), RAD51-Like Protein 1, RecA-Like Protein, Rad51B, PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule
    Entrez ID:
    29126; 5890
    Related biomarkers:
    Expression
    Mutation
    CNA
    Others
    over4years
    [VIRTUAL] RAD51Bme as predictive biomarker for PD-1 blockade response in non-small cell lung cancer. (ASCO 2020)
    We demonstrated that RAD51Bme levels might be combined with validated predictive biomarker PD-L1 immunostaining to select patients who will most likely experience clinical benefit from PD-1 blockade. The predictive value of RAD51Bme should be confirmed in prospective studies. Research Funding: Centro Investigação do IPO Porto
    PD(L)-1 Biomarker • IO biomarker
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    PD-L1 (Programmed death ligand 1) • RAD51B (RAD51 Paralog B)
    |
    PD-L1 expression • RAD51B promoter methylation + PD-L1 expression