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BIOMARKER:

RAD51B promoter methylation + PD-L1 expression

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Other names: RAD51B, RAD51 Paralog B, DNA Repair Protein RAD51 Homolog 2, RAD51 Homolog B, RAD51L1, R51H2, RAD51 Homolog B (S. Cerevisiae), RAD51 (S. Cerevisiae)-Like 1, RAD51-Like 1 (S. Cerevisiae), RAD51-Like Protein 1, RecA-Like Protein, Rad51B, PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule
Entrez ID:
Related biomarkers:
almost4years
[VIRTUAL] RAD51Bme as predictive biomarker for PD-1 blockade response in non-small cell lung cancer. (ASCO 2020)
We demonstrated that RAD51Bme levels might be combined with validated predictive biomarker PD-L1 immunostaining to select patients who will most likely experience clinical benefit from PD-1 blockade. The predictive value of RAD51Bme should be confirmed in prospective studies. Research Funding: Centro Investigação do IPO Porto
PD(L)-1 Biomarker • IO biomarker
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PD-L1 (Programmed death ligand 1) • RAD51B (RAD51 Paralog B)
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PD-L1 expression • RAD51B promoter methylation + PD-L1 expression