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    BIOMARKER:

    QPRT expression

    i
    Other names: QPRT, Quinolinate Phosphoribosyltransferase, QPRTase, Nicotinate-Nucleotide Pyrophosphorylase (Carboxylating), Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating], Quinolinate Phosphoribosyltransferase [Decarboxylating], Epididymis Secretory Sperm Binding Protein Li 90n, HEL-S-90n, QAPRTase
    Entrez ID:
    23475
    Related biomarkers:
    Expression
    over2years
    A comprehensive analysis of the role of QPRT in breast cancer. (PubMed, Sci Rep)
    QPRT was associated with tumour immunity, especially in macrophages. QPRT may influence the occurrence and progression of breast cancer through the PI3K-AKT signalling pathway, Wnt signalling pathway, and cell cycle-related molecules.
    Journal
    |
    HER-2 (Human epidermal growth factor receptor 2) • QPRT (Quinolinate Phosphoribosyltransferase)
    |
    HER-2 expression • QPRT expression • QPRT overexpression
    almost4years
    Increased Expression of QPRT in Breast Cancer Infers a Poor Prognosis and Is Correlated to Immunocytes Infiltration. (PubMed, J Healthc Eng)
    Taking all factors into consideration, the rise in QPRT expression is related to a good prognosis and a grown proportion of immune cells in BRCA, such as neutrophils, B cells, mast cells, and T cells. These results suggest that QPRT can be used to be a possible biological indicator to evaluate the immune infiltration level of BRCA and its prognosis.
    Journal • BRCA Biomarker
    |
    QPRT (Quinolinate Phosphoribosyltransferase)
    |
    QPRT expression
    almost4years
    QPRT Acts as an Independent Prognostic Factor in Invasive Breast Cancer. (PubMed, J Oncol)
    QPRT is highly expressed in breast cancer and particularly in HER2 breast cancer. Upregulated QPRT expression is an independent predictor of breast cancer prognosis and promotes breast cancer progression by activating the PI3K/Akt signalling pathway.
    Journal • BRCA Biomarker
    |
    HER-2 (Human epidermal growth factor receptor 2) • BRCA (Breast cancer early onset) • QPRT (Quinolinate Phosphoribosyltransferase)
    |
    QPRT expression