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over1year
Towards a New Horizon in Prostate Cancer: PSMA-Targeted Docetaxel-Conjugated Nanomedicines for Intratumoral Treatment in Xenograft Model (AUA 2023)
Docetaxel-conjugated mesoporous silica nanomedicines effectively reduced tumor volume in intratumoral administration using a nude mice PC xenograft model. These results are promising, paving the way for a future applicability as a precision intratumoral medicine for PC in humans.
Preclinical
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FOLH1 (Folate hydrolase 1)
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FOLH1 expression • FOLH1 overexpression
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PSMA-targeted docetaxel (BIND-014)