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    BIOMARKER:

    PRMT7 deletion

    i
    Other names: PRMT7, Protein Arginine Methyltransferase 7, KIAA1933, [Myelin Basic Protein]-Arginine N-Methyltransferase PRMT7, Histone-Arginine N-Methyltransferase PRMT7, Protein Arginine N-Methyltransferase 7, FLJ10640, SBIDDS
    Entrez ID:
    54496
    almost4years
    Arginine Methyltransferase PRMT7 Deregulates Expression of RUNX1 Target Genes in T-Cell Acute Lymphoblastic Leukemia. (PubMed, Cancers (Basel))
    Among them was RUNX1, whose target gene expression was consequently deregulated. These results suggest that PRMT7 plays an active role in the pathogenesis of T-ALL.
    Journal
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    RUNX1 (RUNX Family Transcription Factor 1) • PRMT7 (Protein Arginine Methyltransferase 7)
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    PRMT7 deletion