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DRUG:

prednisone

Company:
Generic mfg.
Drug class:
Steroid receptor agonist
2d
TREAT-OMG: TheRapeutic Effect of Different immunosuppressAnts on Non-Thymoma Ocular Myasthenia Gravis: a Real-world Study (clinicaltrials.gov)
P=N/A, N=200, Recruiting, Tang-Du Hospital | Trial completion date: Nov 2024 --> Jun 2026 | Trial primary completion date: Nov 2024 --> Apr 2026
Trial completion date • Trial primary completion date • Real-world evidence
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prednisone
2d
Safe Effective Therapy With Low-Dose Glucocorticoid in ANCA-Associated Vasculitis (SAFE-LOW) (clinicaltrials.gov)
P3, N=36, Recruiting, Ottawa Hospital Research Institute | Not yet recruiting --> Recruiting | Initiation date: Aug 2025 --> Nov 2025
Enrollment open • Trial initiation date
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Rituxan (rituximab) • cyclophosphamide • prednisone
3d
New trial
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Rituxan (rituximab) • prednisone • dexamethasone injection
3d
New trial
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Rituxan (rituximab) • cyclophosphamide • prednisone • Marqibo (vincristine liposomal) • Duoenda (mitoxantrone liposomal) • vindesine
3d
New trial
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prednisone
3d
New P4 trial
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prednisone • AiSuDa (ivarmacitinib)
3d
Study on the efficacy and safety of abiraterone acetate tablets (II) + ADT + chemotherapy in first-line treatment of mCRPC (ChiCTR2500111854)
P4, N=36, Not yet recruiting, Affiliated Hospital of Guizhou Medical University; Affiliated Hospital of Guizhou Medical University
New P4 trial
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docetaxel • abiraterone acetate • prednisone
3d
A single-center exploratory study on the efficacy and safety of tetrandrine tablets in the treatment of interstitial lung disease associated with rheumatoid arthritis (ChiCTR2500107574)
P=N/A, N=60, Recruiting, The First Affiliated Hospital of Army Medical University (Southwest Hospital); The First Affiliated Hospital of Army Medical University (Southwest Hos | Not yet recruiting --> Recruiting | Initiation date: Aug 2025 --> Nov 2025
Enrollment open • Trial initiation date
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Rituxan (rituximab) • cyclophosphamide • prednisone • hydroxychloroquine • tofacitinib • CBT-1 (tetrandrine)
5d
Cutaneous and Systemic Complications in Primary CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma. (PubMed, Cureus)
We present the case of a 61-year-old man with CD8+ AECTCL who developed a methicillin-sensitive Staphylococcus aureus port-site infection while on duvelisib following prior gemcitabine/liposomal doxorubicin therapy...Complement studies supported the activation of the alternative pathway, and after multidisciplinary discussion, eculizumab was initiated for TMA management...His cutaneous lymphoma lesions improved with a short course of oral prednisone as directed by oncology. At discharge, he was clinically stable on dialysis with plans for ongoing outpatient care; subsequent follow-up showed stable renal function. This case highlights the intersection between aggressive cutaneous lymphoma, infection, and chemotherapy-induced vascular injury, emphasizing the importance of early recognition of systemic complications in CD8+ AECTCL and the need for a multidisciplinary approach to optimize patient outcomes.
Journal
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CD8 (cluster of differentiation 8)
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Copiktra (duvelisib) • prednisone
6d
Corticosteroid Effect on Achalasia Variant EGJOO (clinicaltrials.gov)
P1, N=12, Active, not recruiting, Baylor Research Institute | Trial completion date: Jan 2026 --> Nov 2026 | Trial primary completion date: Jan 2026 --> Nov 2026
Trial completion date • Trial primary completion date
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prednisone
7d
Risk factors and outcomes for steroid-refractory immune-related hepatotoxicity in locally advanced and metastatic cancer. (PubMed, Cancer Immunol Immunother)
Patients with Ref-IRH were unlikely to quickly recover with a longer time from initial diagnosis of IRH to resolution to grade 1 (p = 0.002), from peak ALT (p = 0.007), AST (p = 0.011), and TBIL (p = 0.048) to resolution to grade 1, from initial diagnosis of IRH to use of prednisone ≤ 20 mg/day (p = 0.025), and prolonged hospital length of stay (p = 0.017). In conclusion, high IL-6 at diagnosis is a potential risk factor for the development of Ref-IRH. There was no significant difference in efficacy and survival between patients with Ref-IRH and Res-IRH, but much more time from the initial diagnosis of IRH to resolution to grade 1 and the use of immunosuppressive agents is needed for Ref-IRH patients.
Retrospective data • Journal • IO biomarker
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IL6 (Interleukin 6)
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prednisone
7d
Abiraterone With Discontinuation of Gonadotropin-Releasing Hormone Analogues in Metastatic Prostate Cancer (clinicaltrials.gov)
P2, N=31, Completed, Montefiore Medical Center | Active, not recruiting --> Completed
Trial completion • First-in-human
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abiraterone acetate • prednisone