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    BIOMARKER:

    PPARG positive

    i
    Other names: PPARG, Peroxisome Proliferator Activated Receptor Gamma, Peroxisome Proliferator-Activated Receptor Gamma, Nuclear Receptor Subfamily 1 Group C Member 3, PAR-Gamma, NR1C3, Peroxisome Proliferator-Activated Nuclear Receptor Gamma Variant 1, Peroxisome Proliferative Activated Receptor Gamma, PPARgamma, PPARG1, PPARG2 3, CIMT1, GLM1
    Entrez ID:
    5468
    Related biomarkers:
    Mutation
    over2years
    PDK4 – a novel prognostic marker for prostate cancer (EACR 2022)
    Interestingly, PDK4 expression directly corresponds with the metabolic shifts taking place throughout progression from normal prostate tissue to primary and metastatic PCa. To further understand the regulatory network of PDK4 expression and determine therapeutical targets, we will validate these results in our in vitro and in vivo model systems.
    STAT3 (Signal Transducer And Activator Of Transcription 3) • PDK4 (Pyruvate Dehydrogenase Kinase 4) • PPARG (Peroxisome Proliferator Activated Receptor Gamma) • SNAI2 (Snail Family Transcriptional Repressor 2)
    |
    PPARG positive
    3years
    Molecular Signature Expands the Landscape of Driver Negative Thyroid Cancers. (PubMed, Cancers (Basel))
    Both negative groups showed distinct BRS, ERK, and TDS scores, tumor mutation burden, signaling pathways and immune cell profile. Altogether, here we report novel gene variants and describe cancer-related pathways that might impact preoperative diagnosis and provide insights into thyroid tumor biology.
    Journal • Tumor Mutational Burden
    |
    BRAF (B-raf proto-oncogene) • TMB (Tumor Mutational Burden) • LRP1B (LDL Receptor Related Protein 1B) • NUP98 (Nucleoporin 98 And 96 Precursor 2) • SPOP (Speckle Type BTB/POZ Protein) • NCOR1 (Nuclear Receptor Corepressor 1) • PPARG (Peroxisome Proliferator Activated Receptor Gamma) • PAX8 (Paired box 8) • SOS1 (SOS Ras/Rac Guanine Nucleotide Exchange Factor 1)
    |
    BRAF V600E • BRAF V600 • PPARG positive