^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    BIOMARKER:

    POLG2 expression

    i
    Other names: POLG2, DNA Polymerase Gamma 2, Accessory Subunit, MTPOLB, Polymerase (DNA Directed), Gamma 2, Accessory Subunit, DNA Polymerase Subunit Gamma-2, Mitochondrial, DNA Polymerase Gamma Accessory 55 KDa Subunit, Polymerase (DNA) Gamma 2, Accessory Subunit, HP55, P55, Mitochondrial DNA Polymerase, Accessory Subunit, Mitochondrial DNA Polymerase Accessory Subunit, Mitochondrial DNA Polymerase Subunit Gamma-2, POLG-BETA, PolG-Beta, MTDPS16, MtPolB, PEOA4, POLGB, POLB
    Entrez ID:
    11232
    almost2years
    Interference with mitochondrial metabolism could serve as a potential therapeutic strategy for advanced prostate cancer. (PubMed, PLoS One)
    In summary, our findings indicate that over-expressed POLG2 renders poor prognosis in advanced prostate cancer. This disadvantageous factor can serve as a potential indicator, making it possible to target mitochondrial metabolism to treat advanced prostate cancer.
    Journal • Metastases
    |
    POLG2 (DNA Polymerase Gamma 2, Accessory Subunit)
    |
    POLG2 expression
    over4years
    [VIRTUAL] Silencing DNA Polymerase ? induces aneuploidy as a biomarker of poor prognosis in oral squamous cell cancer (AHNS 2021)
    After depletion of POLB expression, OSCC cells induced chromosomal instability and aneuploidy. Altogether, we have identified DNA polymerases beta as an important maintainer of karyotypic stability in OSCC cells.
    POLG2 (DNA Polymerase Gamma 2, Accessory Subunit)
    |
    POLG2 expression
    almost5years
    Silencing DNA Polymerase β Induces Aneuploidy as a Biomarker of Poor Prognosis in Oral Squamous Cell Cancer. (PubMed, Int J Mol Sci)
    After POLB depletion, OSCC cells showed chromosomal instability and aneuploidy. Thus, POLB is an important maintainer of karyotypic stability in OSCC cells.
    Journal
    |
    POLG2 (DNA Polymerase Gamma 2, Accessory Subunit)
    |
    POLG2 expression