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DRUG:

piperacillin

Associations
Trials
Company:
Generic mfg.
Drug class:
PBPs inhibitor
Associations
Trials
5ms
An unusual follicular dendritic cell sarcoma with liver metastasis. (PubMed, Clin Res Hepatol Gastroenterol)
Piperacillin may prove to be a targeted drug with the potential to influence patient prognosis. During the three-month follow-up period following asymptomatic discharge, the patient's condition remained stable. The genetic testing of surgical resection specimens to determine subsequent treatment plans may represent a future treatment strategy.
Journal
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CDKN2A (Cyclin Dependent Kinase Inhibitor 2A)
|
piperacillin
6ms
Multi-Omics Integration with Machine Learning and Molecular Docking Reveals Crosstalk Mechanisms and Drug Candidates in Metastatic Melanoma and Vitiligo. (PubMed, Clin Cosmet Investig Dermatol)
Methyl-angolensate, byssochlamic-acid, homoharringtonine, piperacillin and cephaeline were potentially targeted therapeutic compounds for hub genes based on molecular docking. Our study firstly provides new insight into the genetic crosstalk between metastatic melanoma and vitiligo that may facilitate the development of personalized treatments.
Journal
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NOTCH3 (Notch Receptor 3) • PTPRF (Receptor-type tyrosine-protein phosphatase F) • GJB3 (Gap Junction Protein Beta 3) • PKP1 (Plakophilin 1) • PTK6 (Protein Tyrosine Kinase 6)
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Synribo (omacetaxine mepesuccinate) • piperacillin
7ms
New P2 trial
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HER-2 (Human epidermal growth factor receptor 2) • ER (Estrogen receptor)
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HER-2 positive • ER positive
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Herceptin (trastuzumab) • Ibrance (palbociclib) • Perjeta (pertuzumab) • exemestane • piperacillin
11ms
New P1 trial
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Ibrance (palbociclib) • piperacillin
1year
Clinical analysis of 45 cases of chronic respiratory failure treated by noninvasive ventilator combined with bronchodilator and anti-infective drugs. (PubMed, Eur J Med Res)
A noninvasive ventilator combined with tiotropium bromide and piperacillin has accurate efficacy in the treatment of patients with chronic respiratory failure, which can improve the indexes of arterial blood gas and lung function, reduce inflammatory response, promote disease recovery and have high safety.
Clinical • Journal
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TNFA (Tumor Necrosis Factor-Alpha) • CRP (C-reactive protein)
|
piperacillin
almost3years
Toxicity evaluation of choline ionic liquid-based nanocarriers of pharmaceutical agents for lung treatment. (PubMed, J Biomed Mater Res B Appl Biomater)
In vitro cytotoxicity evaluation of linear copolymer (LC) containing choline ionic liquid units and its conjugates with an antibacterial drug in anionic form, that is, p-aminosalicylate (LC_PAS), clavulanate (LC_CLV), or piperacillin (LC_PIP) was carried out...The MTT test allowed the designation of IC index, which was higher for BEAS-2B, and significantly lower in the case of cancer cell lines. The cytometric analyzes, that is, Annexin-V FITC apoptosis assay and cell cycle analysis as well as gene expression measurements for interleukins IL6 and IL8 were carried out, and showed pro-inflammatory activity of tested compounds toward cancer cells, while it was not observed against normal cell line.
Journal
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IL6 (Interleukin 6) • CXCL8 (Chemokine (C-X-C motif) ligand 8) • ANXA5 (Annexin A5)
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piperacillin
over3years
Primary esophageal diffuse large B-cell lymphoma. (PubMed, Rev Esp Enferm Dig)
Empirical treatment with piperacillin/tazobactan was started...A treatment with Rituximab in combination with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) was started...With the clinical application of ultrasound-guided biopsy, great progress has been made in the diagnostic accuracy and in the evaluation of the depth of invasion in gastrointestinal tumors (2, 4). Physicians should be vigilant for this tumour in individuals presenting with consistent clinical features, as the response to prompt chemotherapy with or whitout radiotherapy is considerably good (5).
Journal
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MME (Membrane Metalloendopeptidase)
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Rituxan (rituximab) • doxorubicin hydrochloride • cyclophosphamide • vincristine • prednisone • piperacillin
almost4years
Ceftazidime and cefepime antagonize 5-fluorouracil's effect in colon cancer cells. (PubMed, BMC Cancer)
This study shows that CFP and CFT have adverse effects on 5-FU's action while CFT is a potent anticancer agent that inhibits DLD-1 cells by inducing apoptotic cell death. Further studies are needed to decipher the mechanism(s) responsible for CFT's effects against colon cancer as well as the observed antagonism between CFT, CFP, and 5-FU with the ultimate aim of translating the findings to the clinical settings.
Journal
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CASP3 (Caspase 3) • CASP7 (Caspase 7)
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5-fluorouracil • piperacillin
almost5years
Oxaliplatin-related interstitial pneumonia with high-grade fever and relative bradycardia as the presenting signs: a case report. (PubMed, J Med Case Rep)
Although cases of oxaliplatin-related pneumonia with complicating relative bradycardia are not uncommon, drug-induced interstitial pneumonia should be taken into account in the differential diagnosis. In this case, an increased circulating eosinophil count and high-grade fever with relative bradycardia were the first signs of drug-induced interstitial pneumonia.
Clinical • Journal
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CD8 (cluster of differentiation 8) • CD4 (CD4 Molecule)
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Avastin (bevacizumab) • oxaliplatin • piperacillin • prednisolone