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    BIOMARKER:

    PIK3R1 M326I

    i
    Entrez ID:
    5295
    Related biomarkers:
    Expression
    Mutation
    Others
    over2years
    Conjunctival Melanoma in Ireland – a sixty year review (ECP 2022)
    Conjunctival melanoma is a rare neoplasm with only 72 cases diagnosed in Ireland in the last 60 years. Recurrence and metastases are common. Options for treatment of conjunctival melanoma include excision, cryotherapy, corneal epitheliectomy, radiotherapy and topical mito-mycin C. Adjuvant therapy is limited, with conjunctival melanomas showing intermediate sensitivity to immunotherapy.
    Review • IO biomarker
    |
    BRAF (B-raf proto-oncogene) • PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) • NRAS (Neuroblastoma RAS viral oncogene homolog) • PIK3R1 (Phosphoinositide-3-Kinase Regulatory Subunit 1)
    |
    PIK3CA mutation • PIK3R1 mutation • PIK3R1 M326I