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GENE:

PIGF (Phosphatidylinositol Glycan Anchor Biosynthesis Class F)

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Other names: PIGF, Phosphatidylinositol Glycan Anchor Biosynthesis Class F, Phosphatidylinositol-Glycan Biosynthesis Class F Protein, GPI11 Homolog, PIG-F, Phosphatidylinositol Glycan, Class F
1year
Dialysis and lyophilization of the mesenchymal stromal cell secretome for wound healing. (PubMed, Cytotherapy)
Dialysis followed by lyophilization is a simple and cost-effective method to fractionate and enrich the bioactive components of MSC-S without compromising the bioactivity for tailor-made applications.
Journal
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IL6 (Interleukin 6) • TNFA (Tumor Necrosis Factor-Alpha) • CXCL8 (Chemokine (C-X-C motif) ligand 8) • PIGF (Phosphatidylinositol Glycan Anchor Biosynthesis Class F) • CD31 (Platelet and endothelial cell adhesion molecule 1) • PECAM1 (Platelet And Endothelial Cell Adhesion Molecule 1)
over1year
Targeting exercise-related genes and placental growth factor for therapeutic development in head and neck squamous cell carcinoma. (PubMed, Front Pharmacol)
This study provides new insights into the molecular mechanisms underlying HNSCC and identifies exercise-related genes, particularly PIGF, as promising biomarkers for clinical treatment and personalized medicine. By focusing on PTMs and their role in cancer progression, our findings suggest that targeting PIGF may offer innovative therapeutic strategies.
Journal
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PIGF (Phosphatidylinositol Glycan Anchor Biosynthesis Class F)
over4years
PIGF and Flt-1 on the surface of macrophages induces the production of TGF-β1 by polarized tumor-associated macrophages to promote lung cancer angiogenesis. (PubMed, Eur J Pharmacol)
The surface molecule PIGF of lung cancer cells could bind to the receptor Flt-1 on the surface of macrophages, thereby increasing the production of TGF-β1, and ultimately promoting the formation of angiogenesis in lung cancer.
Journal
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FLT1 (Fms-related tyrosine kinase 1) • CD163 (CD163 Molecule) • PIGF (Phosphatidylinositol Glycan Anchor Biosynthesis Class F) • TGFB1 (Transforming Growth Factor Beta 1)