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BIOMARKER:

PI16 overexpression

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Other names: PI16 , Peptidase Inhibitor 16, Microseminoprotein, Beta-Binding Protein, Cysteine-Rich Secretory Protein 9, Protease Inhibitor 16, PSP94-Binding Protein, CRISP9, MSMBBP, CD364, PSPBP, CD364 Antigen, DJ90K10.5, MGC45378, CRISP-9
Entrez ID:
over2years
Peptidase inhibitor (PI16) impairs bladder cancer metastasis by inhibiting NF-κB activation via disrupting multiple-site ubiquitination of NEMO. (PubMed, Cell Mol Biol Lett)
These results indicate that PI16 functions as a tumour suppressor in BLCA by inhibiting tumour growth and metastasis. Additionally, PI16 may serve as a potential biomarker for metastatic BLCA.
Journal
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ANXA1 (Annexin A1) • PI16 (Peptidase Inhibitor 16)
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PI16 overexpression