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BIOMARKER:

PD-L1 overexpression + TMB-H

i
Other names: PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule, TMB | Tumor Mutational Burden
Entrez ID:
Related biomarkers:
almost3years
A Ferroptosis-Related Gene Prognostic Index to Predict Temozolomide Sensitivity and Immune Checkpoint Inhibitor Response for Glioma. (PubMed, Front Cell Dev Biol)
A total of 15 potential small molecule compounds (such as depactin, physostigmine, and phenacetin) were identified. FRGPI is a promising gene panel for predicting the prognosis, immune characteristics, temozolomide sensitivity, and ICI response in patients with glioma.
Journal • Checkpoint inhibition • Tumor Mutational Burden • MSi-H Biomarker • PD(L)-1 Biomarker • IO biomarker
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PD-L1 (Programmed death ligand 1) • TMB (Tumor Mutational Burden) • MSI (Microsatellite instability) • CD4 (CD4 Molecule) • HMOX1 (Heme Oxygenase 1) • SOCS1 (Suppressor Of Cytokine Signaling 1)
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PD-L1 expression • TMB-H • MSI-H/dMMR • PD-L1 overexpression • PD-L1 overexpression + TMB-H
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temozolomide