BRCA Biomarker • PARP Biomarker • IO biomarker
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BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset) • PBRM1 (Polybromo 1) • MUC1 (Mucin 1) • IDO1 (Indoleamine 2,3-dioxygenase 1) • STING (stimulator of interferon response cGAMP interactor 1) • IRF1 (Interferon Regulatory Factor 1) • STAT1 (Signal Transducer And Activator Of Transcription 1) • IFIH1 (Interferon Induced With Helicase C Domain 1)
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BRCA1 mutation • BRCA wild-type • PBRM1 mutation • MUC1 expression • IRF1 expression
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Lynparza (olaparib) • carboplatin • P-MUC1C-ALLO1