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    DRUG:

    opolimogene capmilisbac (ADU-741)

    i
    Other names: ADU-741, JNJ-64041809 , JNJ 64041809, JNJ-809
    Associations

    News

    Trials
    Company:
    Novartis
    Drug class:
    Immunostimulant
    Related drugs:
    Associations

    News

    Trials
    over3years
    Safety and preliminary immunogenicity of JNJ-64041809, a live-attenuated, double-deleted Listeria monocytogenes-based immunotherapy, in metastatic castration-resistant prostate cancer. (PubMed, Prostate Cancer Prostatic Dis)
    JNJ-809 has manageable safety consistent with other LADD Lm-based therapies. Limited antigen-specific immune responses were observed, which did not translate into objective clinical responses.
    Clinical • Journal
    |
    IFNG (Interferon, gamma) • TNFA (Tumor Necrosis Factor-Alpha) • IL10 (Interleukin 10)
    |
    opolimogene capmilisbac (ADU-741)
    over6years
    Safety & Immunogenicity of JNJ-64041809, a Live Attenuated Double-deleted Listeria Immunotherapy, in Participants With Metastatic Castration-resistant Prostate Cancer (clinicaltrials.gov)
    P1; N=26; Completed; Sponsor: Janssen Research & Development, LLC; Active, not recruiting --> Completed
    Trial completion
    |
    opolimogene capmilisbac (ADU-741)