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DRUG:

ondansetron

i
Other names: GR 38032F
Associations
Company:
Generic mfg.
Drug class:
Serotonin 3 receptor antagonist
Associations
2d
PIONFORM: Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic Cholecystectomy (clinicaltrials.gov)
P4, N=40, Active, not recruiting, Instituto Mexicano del Seguro Social | Enrolling by invitation --> Active, not recruiting
Enrollment closed
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ondansetron
25d
Kirsten rat sarcoma G12C inhibitor treatment for a patient with relapsed metastatic lung adenocarcinoma: A case report. (PubMed, World J Clin Cases)
After multiple-line treatment including chemotherapy, targeted therapy, and immunotherapy, disease control was achieved in a case of advanced pulmonary adenocarcinoma carrying the KRAS G12C mutation by mutation-specific inhibitor therapy, and the adverse reactions to the therapy were tolerable.
Preclinical • Journal • IO biomarker
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KRAS (KRAS proto-oncogene GTPase)
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KRAS mutation
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Avastin (bevacizumab) • cisplatin • docetaxel • Focus V (anlotinib) • Tyvyt (sintilimab) • albumin-bound paclitaxel • pemetrexed • Kaitanni (cadonilimab) • Aqupla (nedaplatin) • ondansetron
28d
Evaluation of Postoperative Pain Control in Ear Surgery (clinicaltrials.gov)
P=N/A, N=56, Recruiting, Kocaeli University | Not yet recruiting --> Recruiting
Enrollment open
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ondansetron
1m
The Nonirritating Concentrations of Midazolam, Ketamine, and Ondansetron (clinicaltrials.gov)
P4, N=60, Recruiting, Mayo Clinic | Not yet recruiting --> Recruiting
Enrollment open
|
ondansetron
1m
PIONFORM: Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic Cholecystectomy (clinicaltrials.gov)
P4, N=40, Enrolling by invitation, Instituto Mexicano del Seguro Social | Not yet recruiting --> Enrolling by invitation | Trial completion date: Dec 2025 --> Mar 2026 | Trial primary completion date: Dec 2025 --> Mar 2026
Enrollment open • Trial completion date • Trial primary completion date
|
ondansetron
1m
Prophylactic Analgesic and Antiemetic Regimen for Medical Abortion < 70 Days (clinicaltrials.gov)
P1, N=8, Terminated, Hackensack Meridian Health | N=168 --> 8 | Recruiting --> Terminated; Inability to recruit and staffing changes
Enrollment change • Trial termination
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ondansetron
1m
KetHead: Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches (clinicaltrials.gov)
P3, N=56, Recruiting, University Health Network, Toronto | Trial completion date: Feb 2026 --> Jun 2026 | Trial primary completion date: Oct 2025 --> Feb 2026
Trial completion date • Trial primary completion date
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ondansetron
2ms
Efficacy and safety of oliceridine in peri-operative analgesia for patients with urethral stricture: A single-center, randomized, double-blind, positive drug standard-controlled clinical trial (The OliUS Trial) (ChiCTR2500109984)
P=N/A, N=188, Not yet recruiting, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; Shanghai Sixth People's Hospital Affiliated to Shangh
New trial
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Sufenta (sufentanil) • ondansetron
2ms
The prevention of postoperative nausea and vomiting following general anesthesia and the monitoring of intraoperative QTc safety (ChiCTR2500109721)
P4, N=420, Not yet recruiting, Wang Chenggang(Study sponsor); Shanxi Provincial Hospital of Traditional Chinese Medicine / Shanxi Provincial Institute of Traditional Chinese Medicin
New P4 trial
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Sufenta (sufentanil) • olanzapine • ondansetron
2ms
A real-world study on the application of oral aprepitant combined with ondansetron in the treatment of breast cancer antibody-drug conjugates (ChiCTR2500109080)
P4, N=100, Not yet recruiting, Liaoning Cancer Hospital and Institute; Liaoning Cancer Hospital and Institute
New P4 trial • Real-world evidence
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aprepitant oral • ondansetron
2ms
Clinical research plan on the effect of buccal needle therapy on postoperative analgesia and perioperative sleep in patients undergoing cesarean section (ChiCTR2500108240)
P=N/A, N=90, Not yet recruiting, Sir Run Run Hospital Affiliated to Nanjing Medical University; Sir Run Run Hospital Affiliated to Nanjing Medical University
New trial
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ondansetron
2ms
Clinical Evaluation of the Effect of Low-dose Esketamine on Perinatal Depression Symptoms after Delivery: A Prospective Randomized Controlled Study (ChiCTR2500107385)
P4, N=80, Not yet recruiting, The Second Affiliated Hospital of Guangdong Medical University; The Second Affiliated Hospital of Guangdong Medical University
New P4 trial
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Sufenta (sufentanil) • ondansetron