^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    GENE:

    OAS2 (2’-5’-Oligoadenylate Synthetase 2)

    i
    Other names: OAS2, 2’-5’-Oligoadenylate Synthetase 2, 2’-5’-Oligoadenylate Synthetase 2, 69/71kDa, 2’-5’-Oligoadenylate Synthase 2, P69 OAS / P71 OAS, 2-5A Synthase 2, 2’-5’-Oligoadenylate Synthetase 2 (69-71 KD), (2’-5’)Oligo(A) Synthetase 2, (2-5’)Oligo(A) Synthase 2, P69OAS / P71OAS
    Associations

    News

    Trials
    3years
    piR-36249 and DHX36 together inhibit testicular cancer cells progression by upregulating OAS2. (PubMed, Noncoding RNA Res)
    DHX36 can also bind to OAS2 mRNA, and knockdown of DHX36 increases OAS2 mRNA but downregulates its protein, indicating the enhancing effect of DHX36 on OAS2 protein expression. All these data suggest that piR-36249, together with DHX36, functions in inhibiting the malignant phenotype of testicular cancer cells by upregulating OAS2 protein and that piR-36249 may be used as a suppressor factor to regulate the development of testicular cancer.
    Journal
    |
    OAS2 (2’-5’-Oligoadenylate Synthetase 2)