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DRUG:
inixaciclib (NUV-422)
i
Other names:
NUV-422, NUV422, NUV 422
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Associations
News
Trials
Company:
Nuvation Bio
Drug class:
CDK4 inhibitor, CDK6 inhibitor, CDK2 inhibitor
Related drugs:
‹
palbociclib (222)
abemaciclib (80)
ribociclib (62)
dalpiciclib (11)
DSP-2033 (8)
trilaciclib (3)
PRT3645 (3)
RGT-419B (2)
XZP 3287 (2)
TQB3616 (2)
HX301 (2)
CS3002 (1)
FCN-437 (1)
GLR2007 (1)
PF-07220060 (1)
PF-06873600 (1)
G1T38 (1)
BPI-16350 (1)
AM-5992 (0)
BPI-1178 (0)
FLX925 (0)
FN-1501 (0)
HS-10342 (0)
PF-07224826 (0)
SPH4336 (0)
SRX3177 (0)
SYH2043 (0)
TY-0540 (0)
TY-302 (0)
Undisclosed CDK4/6 inhibitor (0)
XH-30002 (0)
CYC065 (6)
BLU-222 (4)
INX-315 (2)
TG02 (2)
PF-07104091 (1)
AVZO-021 (0)
GW8510 (0)
RLY-2139 (0)
CYC202 (0)
palbociclib (222)
abemaciclib (80)
ribociclib (62)
dalpiciclib (11)
DSP-2033 (8)
trilaciclib (3)
PRT3645 (3)
RGT-419B (2)
XZP 3287 (2)
TQB3616 (2)
HX301 (2)
CS3002 (1)
FCN-437 (1)
GLR2007 (1)
PF-07220060 (1)
PF-06873600 (1)
G1T38 (1)
BPI-16350 (1)
AM-5992 (0)
BPI-1178 (0)
FLX925 (0)
FN-1501 (0)
HS-10342 (0)
PF-07224826 (0)
SPH4336 (0)
SRX3177 (0)
SYH2043 (0)
TY-0540 (0)
TY-302 (0)
Undisclosed CDK4/6 inhibitor (0)
XH-30002 (0)
CYC065 (6)
BLU-222 (4)
INX-315 (2)
TG02 (2)
PF-07104091 (1)
AVZO-021 (0)
GW8510 (0)
RLY-2139 (0)
CYC202 (0)
›
Associations
News
Trials
Filter by
Latest
2years
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors (clinicaltrials.gov)
P1/2, N=72, Terminated, Nuvation Bio Inc. | N=269 --> 72 | Trial completion date: Dec 2023 --> Aug 2022 | Active, not recruiting --> Terminated | Trial primary completion date: Aug 2023 --> Aug 2022; Sponsor decision
2 years ago
Enrollment change • Trial completion date • Trial termination • Trial primary completion date
|
HER-2 (Human epidermal growth factor receptor 2) • CAST (Calpastatin)
|
HER-2 negative • IDH wild-type
|
inixaciclib (NUV-422)
over2years
Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC (clinicaltrials.gov)
P1/2, N=0, Withdrawn, Nuvation Bio Inc. | N=236 --> 0 | Suspended --> Withdrawn
over 2 years ago
Enrollment change • Trial withdrawal • Combination therapy
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative
|
fulvestrant • inixaciclib (NUV-422)
over2years
Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC (clinicaltrials.gov)
P1/2, N=236, Suspended, Nuvation Bio Inc. | Initiation date: Apr 2022 --> Sep 2022 | Recruiting --> Suspended
over 2 years ago
Trial initiation date • Trial suspension • Combination therapy
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative
|
fulvestrant • inixaciclib (NUV-422)
over2years
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors (clinicaltrials.gov)
P1/2, N=269, Active, not recruiting, Nuvation Bio Inc. | Recruiting --> Active, not recruiting
over 2 years ago
Enrollment closed
|
HER-2 (Human epidermal growth factor receptor 2) • CAST (Calpastatin)
|
HER-2 negative • IDH wild-type
|
inixaciclib (NUV-422)
over2years
Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC (clinicaltrials.gov)
P1/2, N=236, Recruiting, Nuvation Bio Inc. | Not yet recruiting --> Recruiting
over 2 years ago
Enrollment open • Combination therapy
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative
|
fulvestrant • inixaciclib (NUV-422)
almost3years
Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC (clinicaltrials.gov)
P1/2, N=236, Not yet recruiting, Nuvation Bio Inc.
almost 3 years ago
New P1/2 trial • Combination therapy
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative
|
fulvestrant • inixaciclib (NUV-422)
over3years
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors (clinicaltrials.gov)
P1/2, N=218, Recruiting, Nuvation Bio Inc. | N=80 --> 218
over 3 years ago
Clinical • Enrollment change
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative
|
inixaciclib (NUV-422)
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