^
Contact us  to learn more about
our Premium Content:  News alerts, weekly reports and conference planners
DRUG:

inixaciclib (NUV-422)

i
Other names: NUV-422, NUV422, NUV 422
Associations
Company:
Nuvation Bio
Drug class:
CDK4 inhibitor, CDK6 inhibitor, CDK2 inhibitor
Associations
2years
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors (clinicaltrials.gov)
P1/2, N=72, Terminated, Nuvation Bio Inc. | N=269 --> 72 | Trial completion date: Dec 2023 --> Aug 2022 | Active, not recruiting --> Terminated | Trial primary completion date: Aug 2023 --> Aug 2022; Sponsor decision
Enrollment change • Trial completion date • Trial termination • Trial primary completion date
|
HER-2 (Human epidermal growth factor receptor 2) • CAST (Calpastatin)
|
HER-2 negative • IDH wild-type
|
inixaciclib (NUV-422)
over2years
Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC (clinicaltrials.gov)
P1/2, N=0, Withdrawn, Nuvation Bio Inc. | N=236 --> 0 | Suspended --> Withdrawn
Enrollment change • Trial withdrawal • Combination therapy
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative
|
fulvestrant • inixaciclib (NUV-422)
over2years
Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC (clinicaltrials.gov)
P1/2, N=236, Suspended, Nuvation Bio Inc. | Initiation date: Apr 2022 --> Sep 2022 | Recruiting --> Suspended
Trial initiation date • Trial suspension • Combination therapy
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative
|
fulvestrant • inixaciclib (NUV-422)
over2years
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors (clinicaltrials.gov)
P1/2, N=269, Active, not recruiting, Nuvation Bio Inc. | Recruiting --> Active, not recruiting
Enrollment closed
|
HER-2 (Human epidermal growth factor receptor 2) • CAST (Calpastatin)
|
HER-2 negative • IDH wild-type
|
inixaciclib (NUV-422)
over2years
Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC (clinicaltrials.gov)
P1/2, N=236, Recruiting, Nuvation Bio Inc. | Not yet recruiting --> Recruiting
Enrollment open • Combination therapy
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative
|
fulvestrant • inixaciclib (NUV-422)
almost3years
New P1/2 trial • Combination therapy
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative
|
fulvestrant • inixaciclib (NUV-422)
over3years
Clinical • Enrollment change
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 negative
|
inixaciclib (NUV-422)